Hugo E. Estrada-González, Servicio de Coloproctología, Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México
Alejandro Vela-Torres, Servicio de Coloproctología, Hospital General de México “Dr. Eduardo Liceaga”, Ciudad de México, México
Jeziel K. Ordóñez-Juárez, Unidad de Fisiología Anorrectal del Servicio de Coloproctología, Hospital General de México “Dr. Eduardo Liceaga”, Ciudad de México, México
Paul E. Solís-Hidalgo, Unidad de Fisiología Anorrectal, Servicio de Coloproctología, Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México
Mildred Philippe-Ponce, Servicio de Coloproctología, Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México
Ernesto Medina-Ávalos, Servicio de Gastroenterología, Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México
Gabriela Rangel-Zavala, Servicio de Gastroenterología, Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México
Fátima Higuera de la Tijera, Servicio de Gastroenterología, Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México
Raquel Y. López-Pérez, Servicio de Endoscopia, Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México
Juan A. Villanueva-Herrero, Unidad de Fisiología Anorrectal, Servicio de Coloproctología, Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México
Billy Jiménez-Bobadilla, Servicio de Coloproctología, Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México
Jorge L. de León-Rendón, Clínica de Enfermedad Inflamatoria Intestinal, Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México
Objective: Severity assessment in chronic idiopathic ulcerative colitis (CIUC) is essential for treatment and follow-up. The C-reactive protein/albumin ratio (CAR) is a promising marker in disease prognosis. To determine the usefulness of CAR as a marker of CIUC severity. Methods: A cross-sectional, relational and analytical study including 97 patients with CIUC. Demographic, clinical and paraclinical data were collected. The CAR was calculated and its correlation or association with disease activity was analyzed using the Truelove and Witts scales, the Mayo endoscopic score and the Riley histologic index. Results: Statistically significant differences (p < 0.05) were found between CAR and the extent of CIUC (p = 0.02) and its clinical or biochemical activity (p < 0.001). A positive correlation was found between the extent of CIUC (r = 0.28; p = 0.02) and clinical or biochemical activity (r = 0.41; p < 0.001). Conclusions: CAR could be a valuable indicator to assess the extent, clinical and biochemical severity of CIUC. These findings support the usefulness of CAR in guiding treatment and follow-up.
Keywords: Chronic idiopathic ulcerative colitis. C-reactive protein/albumin ratio. Truelove and Witts.
