Raúl A. Jiménez-Castillo, Servicio de Gastroenterología y Endoscopia Digestiva, Hospital Universitario Dr. José Eleuterio González, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
Luis A. González-Torres, Servicio de Gastroenterología y Endoscopia Digestiva, Hospital Universitario Dr. José Eleuterio González, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
Oveed Olloqui-Martínez, Departamento de Medicina Interna, Hospital Universitario Dr. José Eleuterio González, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
José M. Yáñez-Reyes, Departamento de Medicina Interna, Hospital Universitario Dr. José Eleuterio González, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
José A. González-González, Servicio de Gastroenterología y Endoscopia Digestiva, Hospital Universitario Dr. José Eleuterio González, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
Joel O. Jáquez-Quintana, Servicio de Gastroenterología y Endoscopia Digestiva, Hospital Universitario Dr. José Eleuterio González, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
Héctor J. Maldonado-Garza, Servicio de Gastroenterología y Endoscopia Digestiva, Hospital Universitario Dr. José Eleuterio González, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
Gabriela E. Aguilar-Díaz, Departamento de Medicina Interna, Hospital Universitario Dr. José Eleuterio González, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
Homero Náñez-Terreros, Departamento de Medicina Interna, Hospital Universitario Dr. José Eleuterio González, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
Carlos A. Cortez-Hernández, Servicio de Gastroenterología y Endoscopia Digestiva, Hospital Universitario Dr. José Eleuterio González, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
Background: Patients with liver cirrhosis are prone to bacterial infections, particularly spontaneous bacterial peritonitis (SBP). Previous studies evaluating the usefulness of non-invasive markers in predicting survival in SBP patients have yielded heterogeneous results. Objective: To assess the utility of the neutrophil-to-lymphocyte ratio (NLR), MELD-Na score, and serum lactate as non-invasive markers for predicting 28-day survival in patients with SBP. Materials and methods: This study employed a descriptive and retrospective design. The optimal cut-off values for MELD-Na, serum lactate, and NLR to predict 28-day mortality and survival were determined using ROC curves. We analyzed the relation of these markers to the presence of acute kidney injury. Results: We included 74 patients with a first episode of SBP. The median age was 55 years. The optimal NLR cut-off to predict mortality was ≥ 9.68, MELD-Na ≥ 27.5, and serum lactate ≥ 3.35. For predicting acute kidney injury, the optimal values were NLR ≥ 9.2 and MELD-Na ≥ 25. Conclusions: MELD-Na, NLR, and serum lactate are easily accessible serum markers that may support the prediction of short-term survival.
Keywords: Spontaneous bacterial peritonitis. Serum markers. Non-invasive diagnosis. Albumin. Creatinine. Inflammation.
